Causes Of Failure Of Local Anaesthesia - OCLAKJ
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Causes Of Failure Of Local Anaesthesia

Causes Of Failure Of Local Anaesthesia. These causes can be classified as: Teeth may receive innervation from more than one nerve trunk ( table 1 ).

Hazards of local anesthesia
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Possible causes for failure to achieve local anaesthesia on skin infiltration include medication failure and local infection. Reasons of failures in dental local anaesthesia can be classified as 1) anatomical, 2) pathological, 3) psychological and 4) poor injection technique (20). Frequently used medications include lidocaine, bupivacaine and levobupivacaine.

Possible Causes Of Failure Are Infection, Wrong Selection Of Local Anesthetic Solution, Technical Mistakes, Anatomical Variations With Accessory Innervation And Anxiety Of The Patient.


These causes can be classified as: The failure rate to achieve adequate anesthesia for the procedure is estimated to be 5 percent to 15 percent. If a patient contains a mutation in the amino acid sequence that codes for the construction of their sodium channels, receptor sites might be negatively impacted to the extent that local anesthesia becomes ineffective [5].

Pathological Reasons For The Failure Of Anesthesia Are Trismus, Infection, Inflammation, And Previous Surgery Or Trauma.


There are also the amnesiac effects of the drugs themselves. Certain genetic syndromes and sodium channel disorders: The anesthetic efficacies of lidocaine and mepivacaine injections are remarkably affected in the teeth with irreversible pulpitis ( dunbar et al 1996 ;

1 It Has Not Been Given Suffient Time To Go Numb.


Genetic variation may be the reason for certain patient’s abnormal receptor sites [4, 5]. Possible causes of failure are infection, wrong selection of local anesthetic solution, technical mistakes, anatomical variations with accessory innervation and anxiety of the patient. Therefore, it is possible that genetic variation that alters the site of action as stated above can be the cause.

This Article Describes Five Different Categories Of Failures And Suggests Ways To Troubleshoot Them.


Today, many types of surgery can be safely and painlessly performed while you are awake. Injection of the anesthetic should take place in amounts large enough, with suitable volume and as close as possible to the nerve. Inflammatory diseases altering the pharmacokinetics and pharmacodynamics of local anesthetics cause a response to decrease and unfavorable effects to increase.

A Possible Cause For Anesthetic Failure


Causes for failure to achieve anaesthesia following injection of local anaesthetics include technical failure, infection, defective medication and also following scorpion bite. Local anesthesia fails in 10% of cases of inferior alveolar nerve block and 7% of all cases of local anesthesia in general practice. Reasons of failures in dental local anaesthesia can be classified as 1) anatomical, 2) pathological, 3) psychological and 4) poor injection technique (20).

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